Vitamin D, specifically in its D3 form (Cholecalciferol), is recognized for its extensive role in health and disease management, encompassing benefits that extend to supporting overall skin health and aiding in the maintenance of strong, healthy nails. Suaad Mohammad Joda AL-Hadrawy (2023) explores the physiological actions of Vitamin D3, highlighting its synthesis in mammalian skin upon exposure to ultraviolet (UV) waves, which occurs endogenously. This vitamin plays a pivotal role in regulating the immune system, including the production of antimicrobial peptides like defensin and cathelicidin, which help control the natural intestinal microbiota and support intestinal barriers.
Moreover, Vitamin D3's anti-inflammatory function is crucial in reducing the production of pro-inflammatory cytokines and increasing anti-inflammatory cytokines within immune cells. This mechanism is vital not only for skin health, offering protection against inflammatory conditions and promoting healing, but also for maintaining the integrity of nails by ensuring a healthy growth environment. The research underscores Vitamin D3's importance in preventing chronic diseases and suggests its potential in treating conditions such as COVID-19, further emphasizing its integral role in maintaining overall health, including that of the skin and nails.
References
